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Lion’s Mane for Dogs: A Fungi for Your Furry Friend’s Mind

Lion’s Mane for Dogs: A Fungi for Your Furry Friend’s Mind cover
Written by Real Mushrooms - Updated: June 14, 2024

This feature about the benefits of Lion’s Mane for dogs was written by Real Mushrooms’ resident Registered Veterinary Technician (RVT), Joni Kamlet. Learn more about Joni’s 20 years of experience in animal care, canine rehabilitation, and pet health product development here.

Lion’s Mane Benefits for Dogs: An Ode

An Ode to Lion’s Mane…

Beloved Lion’s Mane..

You are so good for my brain

You are the mushroom that lit my fungi fire.

The more I learn about you, the more I desire

We now have Lion’s Mane in our Real Mushrooms pet line repertoire…

Ok, clearly I’m not a poet. But I do LOVE Lions Mane! Here is my story why:

Lion’s Mane is my gateway mushroom. It is the mushroom that totally upended my life (in a good way!). Lion’s Mane is my doorway to total mushroom obsession, causing me to leave my former job, buy 5 acres of mushroom filled woodland in Virginia, and campaign Skye Chilton, Dr. Rob Silver and the Real Mushrooms team to let me come work with them on Real Mushrooms’ new veterinary product line.

I came to learn about the wonderful possibilities of Lion’s Mane mushrooms for supporting the mind and cognition of pets in 2020. I was working in product development for a company that was making mushroom supplements. Since then, I have been blown away by the testimonials of pet parents who give this mushroom supplement to their dogs.

Cognitive Benefits of Lion’s Mane

While learning about Lion’s Mane I became very excited about the possibility that it could support dogs with degenerative myelopathy (DM). Similar to Lou Gehrig's disease in humans, DM is a neurodegenrative disease with very few supportive options.

DM slowly attacks a dog’s central nervous system by stripping away the protective coating called myelin. This leads to a breakdown of the white matter in the spine which controls movement. Early signs manifest as dragging of the hind limbs, a kind of “drunken sailor” walk. These dogs eventually lose fecal and urinary continence. Eventually, as the disease progresses, the animal can no longer stand or support their body weight. My background as a Veterinary nurse specializing in canine rehabilitation involved working with many of these DM dogs. I know intimately how frustrating and heartbreaking a disease it is.

In vitro studies of Lion's mane mushroom show that it supports the regeneration of the myelin sheath (1). It was for this reason that I was very excited to see how Lion’s Mane would work with these DM dogs. I encouraged a group of veterinarians I was working with to try the Lion’s Mane supplements with their DM patients.

Truth be told, the feedback on how Lion’s Mane affected dogs with DM was inconclusive, but the overwhelming feedback I got was that the dogs on the Lions Mane products were exhibiting better cognitive function, and it was observable.

WOW-This got my attention! Could Lion’s Mane be beneficial for older dogs showing signs of dementia?

About Canine Cognitive Dysfunction

Canine cognitive dysfunction (CCD) is also known as dog dementia. However, cats can also suffer from this condition. CCD is a growing area of concern in the veterinary community. Just like humans, as animals get older, they can develop Alzheimer’s-type symptoms.

Aging is the main risk factor for CCD with 28% of dogs in the 11–to-12-year-old range, and 68% in dogs 15 years old and higher showing signs of CCD (2). Cats fared a bit better with 36% of 11–to-21-year-old cats displaying signs of dementia. (3)

Canine Cognitive Dysfunction
Much like aging humans, senior dogs and cats can develop a dementia-like condition. Helpfully, Lion’s Mane mushroom supplements are an option for helping to address the symptoms of cognitive dysfunction in pets.

Canine cognitive dysfunction can manifest as the following symptoms:

  • Behavior changes
  • Confusion
  • Disorientation
  • Staring off into space
  • Loss of housebreaking skills
  • Difficulty moving around familiar spaces
  • “Sundowning” (becoming more confused towards end of day)
  • Altered sleep/wake cycles
  • Anxiety
  • Inability to locate dropped food
  • Excessive vocalization, especially at night
  • Apparent hearing loss
  • Diminished interaction with family

Lion’s Mane for Dog Cognition

Let's go back to the group of veterinarians that I mentioned earlier in this blog. Here is some of the feedback I received from them regarding the Lions Mane supplement and how it affected their animal patients with dementia. Please note that this was not a clinical study. This is information that pet parents shared with their veterinarians after using the product for a few weeks.

Improvements noted in dogs:

  • Holding eye contact
  • Finding dog door when they couldn’t previously
  • More engaged with & attentive to owners
  • Not getting lost in house/familiar surroundings
  • Picking up and playing with toys
  • Initiating play with owners
  • Less inappropriate vocalization

Given the fact that Lion's Mane is safe for dogs and cats and mild tasting, I think it's an excellent addition to our veterinary offerings. Since Lion’s Mane powder extract has a subtle seafood flavor, cats should readily take to it.

Senior dog - dementia
Senior pets can experience brain changes that affect their mood, sleep, memory, and even continence. Lion’s Mane mushroom has been studied for its neurological support in humans and pets respond well to this natural solution for old-age care.

A Primer About Lion’s Mane Mushroom

Hericium erinaceus is mostly referred to as Lion’s Mane, but can also be known as hedgehog fungus, monkey head mushroom, pom pom mushroom. This fungus is a good example of the doctrine of signatures, as it resembles a brain.

Currently one of the most popular of functional mushrooms, it is relatively new to researchers since it is quite a rare find in nature. The ability to cultivate it on a large scale commercially for medicinal and culinary use has significantly added to its current popularity. Unfortunately, the relative newness of this fungi on the Western market means fewer completed clinical studies. Sadly, there are no clinical studies in dogs and cats yet. However, there are other animal studies that point to the interesting possibilities for this mushroom to be used for enhancing the quality of cognition in pets.

Fresh Lion's Mane Mushroom
The mushroom that looks like a brain can also help support healthy brain function in humans and pets.

Lion’s Mane for the Gut, Memory, Mood, and the Immune System

Lion’s Mane has been traditionally used in China and Japan as food and medicine to support gut health, nervous system weakness and debility, even wound healing. It is also used to support the spleen, nourish the kidneys and it has an affinity for the lungs. There are clinical studies showing Lion’s Mane can be highly beneficial in relation to inflammatory bowel disease, gastrointestinal issues, and ulcers (4).

One of the great benefits of Lion’s Mane, like the other medicinal mushrooms, is that it is very effective at promoting a health inflammatory response in general. This mushroom is also considered an adaptogen that can help regulate the immune system.

Lion’s Mane has been receiving a lot of attention in relation to its effect on brain function and cognition. This is a relatively new use for this mushroom, and is related to discoveries around its effect on Nerve growth factor (NGF) in the 1990’s. More recent clinical studies have supported this discovery (5).

Human clinical studies have shown Lion's Mane to be anti-depressive and anxiolytic, improving scores on anxiety and depression scales (6). Human studies have also demonstrated that Lion’s Mane can support better memory recall in aging people with mild memory issues (7,8).

I would readily use Lion’s Mane for pets with behavior issues, cognitive dysfunction, any type of GI issues, to support immune health, to support calming. I would definitely use it with DM dogs in spite of the mixed results I received initially.

Learn more about the ways this unique fungus can support health in our article, Lion’s Mane Mushroom Benefits: A Complete Supplement Guide.

Can Dogs Eat Lion’s Mane Mushrooms?

Lion’s Mane is a delicious culinary mushroom that is increasingly available at farmers markets and specialty grocery stores. Like other edible mushrooms that humans can eat, Lion’s Mane is indeed safe for dogs and cats to consume.

However, it is important to cook Lion’s Mane mushroom before giving it to your pet because it can be difficult to digest in raw form.

Now, there is an easier way to serve up this functional mushroom to your pet. If you are hoping to use this mushroom as a means of improving you pet’s health, you can use a concentrated mushroom powder extract.

How to Give Your Dog Lion’s Mane

Real Mushrooms now provides its renowned mushroom powder extracts in a format suitable for giving to pets. Read below for more details about this functional supplement and how to give it to your pet.

Lion’s Mane Supplement for Dogs and Cats

The Organic Lions Mane Extract Capsules for Pets by Real Mushrooms is ideal because it is pre-measured to make it suitable for animal dosing.

The Real Mushrooms line of pet supplements has the same high concentration of beta-glucans as its regular line of mushroom powders. There are no fillers or unnecessary additives and the supplement is made from 100% Lion’s Mane mushroom, not mycelium.

Learn more about how to identify a quality Lion’s Mane extract for your pet by reading our article Find the Best Lion’s Mane Supplement: The 4-Point Buying Guide.

shop real mushrooms for pets

Lion’s Mane Dosage for Dogs and Cats

Conveniently, using Real Mushrooms’ pet-specific Lion’s Mane supplement makes the issue of dosing a breeze.

Dosing: 1 capsule for every 20-40 pounds of body weight or as directed by your veterinarian.

In the case of cats who are difficult to pill, simply break the capsule apart and sprinkle the powder on their food. The mild seafood taste of Lion’s Mane seems to appeal to cats.

Learn more about the benefits of mushrooms and mushroom supplements for dogs and cats in our other pet articles:


  1. Kevin Spelman, Elizabeth Sutherland, Aravind Bagade. December 1, 2017. Neurological Activity of Lion’s Mane (Hericium erinaceus).
  2. Stanislav Katina, Jana Farbakova, Aladar Madari, et al. February 29, 2016. Risk factors for canine cognitive dysfunction syndrome in Slovakia.
  3. Petra Černá, Hannah Gardiner, Lorena Sordo, et al. June 24, 2020. Potential Causes of Increased Vocalisation in Elderly Cats with Cognitive Dysfunction Syndrome as Assessed by Their Owners.
  4. Ali Durmus, Ilgim Durmus, Omer Bender, et al. The effect of Hericium erinaceum on the prevention of chemically induced experimental colitis in rats.
  5. Hirokazu Kawagishi. January 7, 2021. Chemical studies on bioactive compounds related to higher fungi.
  6. Mayumi Nagano, Kuniyoshi Shimizu, Ryuichiro Kondo, et al. August 31, 2010. Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake.
  7. Mori, K., Inatomi, S., Ouchi, K., Azumi, Y., & Tuchida, T. (2009). Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Phytotherapy research : PTR, 23(3), 367–372.
  8. Saitsu, Y., Nishide, A., Kikushima, K., Shimizu, K., & Ohnuki, K. (2019). Improvement of cognitive functions by oral intake of Hericium erinaceus. Biomedical research (Tokyo, Japan), 40(4), 125–131.

Real Mushrooms is the premier provider of organic mushroom extracts, verified for the beneficial medicinal compounds like beta-glucans and free from starchy fillers like grains. With over 40 years of mushroom growing experience, Real Mushrooms prides itself on providing a transparent source of functional mushrooms that you can trust. All the information provided on our blog has been reviewed by our science and medical team.

Disclaimer: The information or products mentioned in this article are provided as information resources only, and are not to be used or relied on to diagnose, treat, cure, or prevent any disease. This information does not create any patient-doctor relationship, and should not be used as a substitute for professional diagnosis and treatment. The information is intended for health care professionals only. The statements made in this article have not been evaluated by the Food and Drug Administration. Any products mentioned are not intended to diagnose, treat, cure, or prevent any disease. The information in this article is intended for educational purposes. The information is not intended to replace medical advice offered by licensed medical physicians. Please consult your doctor or health practitioner for any medical advice.