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Functional Mushroom Benefits for Women & Their Hormonal Health

Functional Mushroom Benefits for Women & Their Hormonal Health cover
Written by Real Mushrooms - Updated: October 7, 2024

We’ve come a long way when it comes to investing in healthcare and improving wellness routines.

Still, there’s no denying that women’s health concerns are often downplayed or overlooked. Women experience unique health challenges, such as pregnancy issues, menopause, increased risk of autoimmune disorders, and certain types of cancers.

We at Real Mushrooms understand the importance of women’s health. That’s why we’re dedicating this article to functional mushroom benefits for women and common concerns about their well-being.

We’ll look at some of the well-studied health benefits of three functional mushrooms: reishi, lion’s mane, and cordyceps. This guide will review how they can help women manage the symptoms of menopause, promote healthy hormone levels, and support fertility.

In This Article

  • Women and Menopause
  • Mushroom Health Benefits for Women in Menopause
  • Mushrooms May Help Balance Hormones
  • Mushrooms May Help With PCOS And Fertility
  • Optimize Women’s Health with Functional Mushrooms
3 mushroom benefits for women
From left to right: dried reishi, lion’s mane, and cordyceps mushrooms and their extract powders. Each of these has properties that can help women manage health concerns unique to them.

Women and Menopause

Menopause is a time of significant changes for women reaching the middle of their lives. It marks the end of menstrual cycles, a result of a steep decline in estrogen and progesterone.

Though inevitable, many women dread perimenopause (the transition period to menopause) and menopause. The fluctuations and eventual cessation of ovarian estrogen and progesterone production lead to symptoms such as:

  • Sleep problems
  • Mood changes
  • Hot flashes
  • Anxiety

In other words, menopause can make women feel like they don’t recognize themselves anymore.

Mushroom Health Benefits for Women in Menopause

If you’re a woman experiencing menopause, there are several things you can do to support your body, including adding edible mushrooms to your diet or taking mushroom extract supplements.

Mushrooms have a savory flavor, making them great for cooking whether you have them as dried mushrooms or chopped mushrooms in dishes. Besides being great for cooking, they also have various health benefits.

When you eat mushrooms and add them to your diet, you’ll enjoy the many health benefits they have to offer, from mushrooms that support healthy aging to those that contain health-boosting vitamins.

Besides adding mushrooms to your diet, substituting mushrooms for certain ingredients like meat and fiber-rich food can also help you stay fit and healthy.

Eating mushrooms with high nutritional value that boost a healthy immune system, help manage healthy blood pressure levels, and help alleviate minor stress can be great for women undergoing menopause.

Among the many functional mushroom varieties available, three stand out as critical choices in supporting women's health in menopause: reishi, cordyceps, and lion’s mane mushrooms.

Let’s look at the mushroom benefits for women experiencing menopause and how three types can help alleviate some common symptoms.

1 - Reishi for Menopause

Reishi (genus Ganoderma) mushrooms seem to be in their own league when it comes to potential health benefits. While there may be as many as 2,000 Ganoderma species, the most common is G. lucidum. 

There have been many historical uses of reishi, from being used in holistic and cultural practices to its potential as a natural remedy. For instance, reishi mushrooms contain bioactive compounds that can help improve sleep, support gut health, and boost brain health.

Let’s examine how reishi can support your body during menopause.

Reishi Helps with Sleep

If you’re going through menopause and can’t sleep, you’re not alone.

Experts estimate around 12% of women experience sleep difficulties, with sleep complaints increasing dramatically among women in their late 40s to early 50s [1]. Because this age range is when women typically transition to menopause, the increase suggests a potential link between sleep disturbances and menopause transition.

Reishi was used in traditional Chinese medicine for its sedative (An-Shen) effect [2,3]. This means regular use of reishi mushrooms could help you not lose sleep from your racing thoughts.

A study in rats showed that reishi decreased sleep latency or the time it takes one to fall asleep. In doing so, reishi increased the rats’ sleeping time, non-rapid eye movement (REM) sleep time, and light sleep time [4].

The findings from this study suggest that the bioactive compounds in reishi may affect the gamma-aminobutyric acid (GABA) pathway. GABA is an inhibitory neurotransmitter known for helping reduce stress and enhancing sleep [5].

A similar study showed the influence of reishi mushroom extracts in rats. Just three days of treatment at 80 mg/kg increased total sleep time and non-REM sleep time [3]. Researchers also found increases in tumor necrosis factor-alpha (TNF-ɑ), a key regulator of sleep [6].

Another way by which reishi promotes sleep may be through the gut microbiome.

A mouse study published in the journal “Scientific Reports” reported that the sleep-promoting effect may be due to a signaling increase in a serotonin-associated pathway in the brain. This effect appears to also be dependent on the health of the gut microbiome, as it disappeared when antibiotics depleted the gut microbiome [7].

These animal studies suggest various mechanisms through which reishi helps promote higher-quality sleep. However, more research will be needed to confirm these findings in human subjects.

Reishi for sleep
Disruption in sleep length and quality is a common feature of menopause. Women can benefit from a high-quality reishi supplement because it can help support a night of restful sleep.

Reishi Helps with Energy

Traditional Chinese medicine physicians call reishi “the mushroom of immortality” for its all-encompassing health support [8]. Let’s examine some research and the health claims of reishi’s connection with fatigue.

A common method used to study anti-tiredness effects in mice is a forced swimming test. Multiple animal studies using this test show a significant anti-fatigue effect in reishi.

For example, a study published in 2012 showed that polysaccharides from reishi extended the exhaustive swimming time of mice. The polysaccharides also displayed their powerful antioxidant qualities in this study by decreasing the blood lactate and serum urea nitrogen contents [9].

Fatigue is also a common side effect associated with medical conditions. A study evaluated the effects of reishi mushroom and carob on women with fibromyalgia. After six weeks of taking 6 grams of reishi daily, the participants showed significantly enhanced physical fitness and up to 30% less pain. The group that took the carob supplements showed no improvements [10].

A preliminary study from Thailand looked at the effects of reishi mushrooms on 50 subjects with chronic fatigue syndrome. The subjects who received the treatment for 12 weeks reported less fatigue and better quality of life [11].

Learn More About Reishi: Interested in learning more about reishi? Check out Reishi Mushroom Benefits & Usage: A Comprehensive Guide.

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2 - Lion’s Mane for Menopause

Lion’s mane (Hericium erinaceus) is known by various nicknames, such as the “monkey head” mushroom or the “pom-pom” mushroom. These mushrooms are easily identified by their long, thin, soft white tendrils that resemble, well, a lion’s mane.

Any discussion about the lion’s mane mushroom would be incomplete without talking about its brain-boosting properties, how it may stimulate brain cell growth, and its impact on overall health. Let’s examine how lion’s mane can help you during menopause.

Lion’s Mane Supports Your Memory

Women are disproportionately affected by Alzheimer’s disease. Experts estimate that out of the 6.5 million Americans living with the disease in 2022, almost two-thirds are women [12].

Researchers are still trying to figure out why, but here’s what we know so far:

  • Women tend to live longer than men.
  • The amyloid plaques that lead to Alzheimer’s disease may actually be a byproduct of the brain’s immune mechanism that protects against fungal and bacterial infections [13].
  • Women are about twice as likely to develop an autoimmune disorder compared to men.
  • Studies show women have stronger immune systems [14].

One Harvard researcher proposed that women’s stronger immune systems may be the reason behind their greater risk for Alzheimer’s disease [15]. Even without this risk, the decline in estradiol — the primary form of estrogen in the brain — can impact memory function.

The good news is there are many things you can do to maintain your brain health regardless of your age. Eating lion’s mane mushrooms or taking extract supplements from this variant can play a part.

Lion's mane mushroom benefits for women
Women’s cognition can take an extra hit from hormone changes as they age. Taking lion’s mane mushrooms as a dietary supplement is a natural way to support brain health.

The brain-supporting properties of lion’s mane are attributed to two highly studied compounds: hericenones and erinacines. These two compounds stimulate the production of nerve growth factors (NGFs).

Research studies have linked NGF deficiency to memory impairments and impaired production of new neurons (neurogenesis) [16].

In a Japanese human clinical trial, subjects were given either a lion’s mane mushroom supplement or a placebo for 12 weeks. Both groups were evaluated using three tests: a mental state exam, a visual retention test, and a verbal paired-associate learning test.

Only the supplement-taking group showed improvements at the end of the trial, demonstrating the potential of lion’s mane to support cognitive function [17].

Another human trial using lion’s mane in menopausal women showed reductions in feelings of anxiety and irritation after four weeks [35].

Learn More About Lion’s Mane: Interested in learning more about lion’s mane? Check out Lion’s Mane Mushroom Benefits: A Complete Supplement Guide.

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3 - Cordyceps for Menopause

The decline in estrogen and progesterone can knock other hormones off balance, resulting in fatigue. As discussed earlier, many women also experience poor sleep quality, which also contributes to fatigue.

Rather than reaching for yet another cup of coffee or an energy drink, cordyceps mushrooms may offer a caffeine-free way to sustain energy. Let’s look at a few well-known properties of cordyceps and how this type of mushroom can benefit women’s health during menopause.

Cordyceps Helps with Energy

Cordyceps mushrooms are popular in traditional Chinese medicine for their invigorating and energy-enhancing qualities.

A clinical trial studied the effects of cordyceps supplementation in 20 healthy elderly subjects. One group received the placebo, and the experimental group received 333 mg of a cordyceps mushroom supplement thrice a day for 12 weeks.

At the end of the study, the subjects who received the cordyceps supplement saw increases in their metabolic threshold and their ventilatory threshold. On the other hand, no significant changes were seen in either threshold for the control group [18].

While there are promising results for the elderly, it’s possible that you won’t experience the energy-enhancing benefits from cordyceps mushrooms if you’re an athlete.

A study involving 22 endurance-trained male athletes showed that cordyceps mushroom supplementation had no effect on endurance or aerobic capacity [19]. The researchers in this study theorized that because trained athletes are already close to their aerobic capacity, cordyceps mushroom supplements wouldn’t have a significant effect.

So, how do cordyceps mushrooms accomplish all of this? Animal and laboratory studies may provide some insight into this question.

One research team studied the effects of a two-week C. militaris supplementation in mice. Administration of the fungi increased Adenosine triphosphate (ATP) levels and antioxidative enzyme activity.

The treated mice had lower levels of lactic acid, lactic dehydrogenase, malondialdehyde, and reactive oxygen species compared to untreated mice. In short, the cordyceps mushroom supplements helped enhance stamina in the treated mice [20].

Do Mushrooms Have Vitamin D?: Some mushrooms contain plenty of vitamin D, making them great for women’s health. Vitamin D supports calcium absorption, promoting stronger bone health.

Cordyceps & Reishi for energy
Women can benefit from taking a cordyceps mushroom supplement to provide energy-enhancing properties, without having to rely on more caffeine.

Cordyceps Can Help with Libido

Your hormone levels taking a nosedive during menopause has another huge impact — a lower sex drive, or libido. You may have a harder time becoming aroused, or you may find that your body isn’t as sensitive to intimate touches as it used to be.

For some women, vaginal dryness resulting from hormonal changes can make sex downright painful [21]. To address this, practitioners of traditional Chinese medicine have long valued cordyceps mushrooms for their effects on sexual functions as one of its many key health benefits.

Few clinical trials investigating the libido-enhancing effects of cordyceps mushrooms have included women.

In one placebo-controlled trial involving elderly patients with decreased libido, an astonishing 86% of women taking a Cordyceps mushroom supplement reported improvements in their sex drive. Even more impressive, this improvement was seen after only 40 days of Cordyceps supplementation [22].

A similar clinical trial involved 189 subjects (men and women) with decreased libido. After 40 days of treatment with Cordyceps mushrooms, 66% of the patients reported improvements compared to just 24% of those who received the placebo [22].

The mechanism for the aphrodisiac activity of cordyceps mushrooms remains unclear. One possibility is that its ability to support testosterone production could benefit women, especially those undergoing perimenopause and menopause [23].

While it may seem counterintuitive, recent studies actually show that adding testosterone to hormonal therapy in women can improve their sexual function, including boosting their sexual desire [24].

Learn More About Cordyceps: Interested in learning more about cordyceps? Check out Cordyceps Mushrooms: Supplement Types & Health Benefits

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Mushrooms May Help Balance Hormones

Hormones are chemical messengers that allow your cells to communicate with one another. The lack of energy and poor sleep quality discussed in the above sections have a common root cause: hormone imbalance.

All women, not just those in menopause or postmenopause, can experience hormonal imbalance. That’s because hormones work together to keep your body in a state of balance, or homeostasis.

Scientists have identified more than 50 hormones so far in the human body, just a few of which include [25,26]:

  • Estrogen
  • Testosterone
  • Insulin
  • Thyroid hormones
  • Progesterone
  • Antidiuretic hormone
  • Cortisol

Hormones influence just about every aspect of your body. That’s why even minor disruptions in their delicate balance can lead to unwanted symptoms like mood swings.

1 - Reishi and Hormone Balance

There are plenty of ways to support healthy hormone levels beyond lifestyle factors like a healthy diet and regular exercise. Research suggests that adaptogens, especially plant-originated ones, can help strengthen the stability of your body’s internal environment and avoid damage [27].

As adaptogens, functional mushrooms like reishi can help support a healthy endocrine system.

Take stress for example: stress and anxiety can increase your cortisol level. This natural, valuable system helps your body respond to immediate threats.

As a woman in our modern society, you likely have to endure unique stress, from the pressures of maintaining your career to childcare. This long-term activation of your stress response system (and overexposure to cortisol) disrupts the balance of your other hormones.

From our discussion, you might have guessed that reishi can help your body adapt to stress.

In one study, scientists explored the adaptogenic potential of reishi in mice using the elevated plus maze model. The researchers found that mice given a reishi extract at a dose of 200 mg/kg showed lower levels of anxiety than those that received a placebo [28].

Reishi has also demonstrated the ability to support estrogen-like activity in cell models and rats, which suggests that it could be useful in regulating estrogen levels [29]. However, further evidence is needed to confirm whether it exhibits similar properties in humans.

Reishi mushroom benefits for women - fatigue
Reishi is a mushroom that can help women manage several symptoms of menopause. It can support better sleep quality and duration, fight fatigue, and can help manage mood and reactions to stress.

Mushrooms May Help with PCOS And Fertility

Polycystic ovarian syndrome (PCOS) is a common hormonal disorder among women, characterized by higher-than-normal levels of androgens and changes in insulin sensitivity. High levels of androgens may interfere with ovulation, lead to the formation of cysts, and produce other symptoms like excess hair growth on the face [30].

Thankfully, studies on maitake and reishi mushrooms have shown promising health benefits that may benefit women with PCOS.

1 - Maitake and PCOS

Another great functional mushroom for women with PCOS is maitake (Grifola frondosa).

Maitake extract monotherapy induced ovulation in nearly 77% of the patients. It also displayed ovulation-inducing abilities when used in combination with clomiphene citrate, a common medication to treat infertility in women [33].

These findings suggest that maitake may induce ovulation in patients with PCOS either as a monotherapy or in combination with other fertility treatments. However, larger trials are needed to confirm these theories.

2 - Reishi and PCOS

Research shows that reishi may have the strongest testosterone-inhibiting activity among other varieties of functional mushrooms. This is due to reishi’s potential to have anti-androgenic effects.

Anti-androgens are compounds that can either block or suppress the action of hormones like testosterone. There has been increasing interest in plant- and fungi-originated anti-androgens as complementary therapies to conventional medications.

A study by Fujita and colleagues compared the 5-alpha-reductase activity of various mushroom species [31]. The enzyme 5-alpha-reductase converts testosterone to dihydrotestosterone, an androgen that stimulates the development of masculine characteristics.

Of the 19 species tested, reishi exhibited the strongest inhibitory activity against 5-alpha-reductase, suggesting it may help promote a healthy hormonal balance.

Mushroom supplements for hormones
Both reishi and maitake mushrooms can help support hormone balance. They can be used as a natural support for healthy ovulation and fertility.

Reishi for Stress-Related Fertility Issues

Chronic stress, obesity, hormonal imbalance, and other factors can increase the risk of infertility. Fortunately, reishi mushrooms can help.

Stress isn’t just “I have a million things to do” stress. It can come to you in various forms, such as pro-inflammatory foods, financial challenges, conflict in relationships, insufficient sleep, etc.

The list of stressors is endless. Thankfully, adaptogens like reishi can help your body adjust to occasional stress and maintain stability.

In addition to promoting better sleep quality, research indicates that reishi can modulate the endocrine organs involved with stress hormone production. This supportive activity may help balance excess stress hormone production [34].

Eat Mushrooms With Variety: The health benefits of mushrooms will vary, depending on what type of mushroom you eat. For example, cremini mushrooms are rich in vitamin D, while shiitake mushrooms is said to have an effect on cholesterol levels.

Optimize Women’s Health with Functional Mushrooms

Women face many unique health challenges that may benefit from the support of functional mushrooms. Before adding mushrooms to your diet and adjusting your wellness routine, we recommend consulting your physician to make sure they’re right for you.

If you don’t have an easy way to get fresh mushrooms or wild mushrooms, you don’t have to forage for yourself to enjoy the health benefits of mushrooms.

If you’re looking for the best functional mushrooms to support your health, look no further than Real Mushrooms supplements. You can be confident in the safety, efficacy, purity, and potency of our products.

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References:

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  17. ‌Saitsu, Y., Nishide, A., Kikushima, K., Shimizu, K., & Ohnuki, K. (2019). Improvement of cognitive functions by oral intake of Hericium erinaceus. Biomedical Research, 40(4), 125-131. https://doi.org/10.2220/biomedres.40.125
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  28. Singh, R., Dhingra, G. S., & Shri, R. (2016). Evaluation of Antianxiety Potential of Four Ganoderma (Agaricomycetes) Species from India in Mice. International Journal of Medicinal Mushrooms, 18(11), 991–998. https://doi.org/10.1615/intjmedmushrooms.v18.i11.40
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  31. Fujita, R., Liu, J., Shimizu, K., Konishi, F., Noda, K., Kumamoto, S., Ueda, C., Tajiri, H., Kaneko, S., Suimi, Y., & Kondo, R. (2005). Anti-androgenic activities of Ganoderma lucidum. Journal of ethnopharmacology, 102(1), 107–112. https://doi.org/10.1016/j.jep.2005.05.041
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  33. Chen, J. T., Tominaga, K., Sato, Y., Anzai, H., & Matsuoka, R. (2010). Maitake mushroom (Grifola frondosa) extract induces ovulation in patients with polycystic ovary syndrome: a possible monotherapy and a combination therapy after failure with first-line clomiphene citrate. Journal of alternative and complementary medicine (New York, N.Y.), 16(12), 1295–1299. https://doi.org/10.1089/acm.2009.0696
  34. ‌Liao, L. Y., He, Y. F., Li, L., Meng, H., Dong, Y. M., Yi, F., & Xiao, P. G. (2018). A preliminary review of studies on adaptogens: comparison of their bioactivity in TCM with that of ginseng-like herbs used worldwide. Chinese medicine, 13, 57. https://doi.org/10.1186/s13020-018-0214-9
  35. Nagano, M., Shimizu, K., Kondo, R., Hayashi, C., Sato, D., Kitagawa, K., & Ohnuki, K. (2010). Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake. Biomedical research (Tokyo, Japan), 31(4), 231–237. https://doi.org/10.2220/biomedres.31.231

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Real Mushrooms is the premier provider of organic mushroom extracts, verified for the beneficial medicinal compounds like beta-glucans and free from starchy fillers like grains. With over 40 years of mushroom growing experience, Real Mushrooms prides itself on providing a transparent source of functional mushrooms that you can trust. All the information provided on our blog has been reviewed by our science and medical team.

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